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The primary endpoint was a composite of death from cardiovascular causes, non-fatal MI or non-fatal stroke, with a significant 20% reduction in the semaglutide group versus placebo

The American and Canadian Colleges of Obstetrics and Gynecology recommend the use of a delayed-release formulation of pyridoxine hydrochloride (vitamin B 6 ) plus doxylamine succinate (an antihistamine) as first-line therapy for nausea and vomiting during pregnancy

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This activation reduced neuroinflammation and restored levels of key synaptic proteins [69]